Stress ulcer prophylaxis: pantoprazole 80 mg IV bolus over 5 minutes followed by an 80 mg IV infusion every 12 hours

Active GI bleeding: pantoprazole 80 mg IV bolus over 5 minutes, followed by a continuous IV infusion of 8 mg/hr for a period of 72 hours or until the bleeding stops (whichever is longer)

Prevention of GI re-bleeding: pantoprazole 80 mg IV bolus over 5 minutes, followed by a continuous IV infusion of 8 mg/hr for a period of 72 hours

In duodenal ulcers, while healing with sucralfate often occurs within 2 to 4 weeks, treatment should be continued for a maximum of 8 to 12 weeks unless healing has been demonstrated by x-ray and/or endoscopic examination.

In the case of gastric ulcers, an alternative treatment should be considered if no objective improvement is observed following 6 weeks of sucralfate therapy. However, patients with a large gastric ulcer that has demonstrated a progressive healing tendency may require an additional 6 weeks of treatment.

For the prophylaxis of duodenal ulcer recurrence, the recommended dosage is 1 g twice daily, on an empty stomach. Treatment may be continued for up to 1 year.

For relief of pain, antacids may be added to the treatment. However, antacids should not be taken within 1/2 hour before or after sucralfate intake.

Suspension Plus (1 g/5 mL): Adults: (Acute) duodenal ulcer: 2 g (10 mL) twice a day on waking and at bedtime on an empty stomach.

Prophylaxis of gastrointestinal hemorrhage due to stress ulceration: 1 g (5 mL) orally or via nasogastric tube 4 to 6 times a day. To prevent clogging of the nasogastric tube flush with 10 mL of water following each administration.

The duration of treatment for prophylaxis of stress ulceration must be individually determined. Treatment should be continued for as long as one or more of the risk factors for stress ulceration is present but normally not for more than 14 days.